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The main differences between Wegovy and other GLP-1 medications are

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Should metformin dose be increased first in a patient with type 2 diabetes mellitus, HbA1c 5.8%, taking metformin 500 mg daily, phentermine, and NP thyroid 60 mg daily, with poor diet and exercise compliance, before considering GLP-1 receptor agonists?

The message to the patient is that we are still investigating if these drugs put them at higher risk of ischemic optic nerve damage

Upregulation of WDR6 drives hepatic de novo lipogenesis in insulin resistance in mice