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Similar to peripheral tissues, brain tissues also transport iron out of cells under the synergistic effect of Fpn/hephaestin and/or Fpn/CP (Li and Qian, 2002

Taken together, all these evidences suggest that the HA biopolymer present in CG has a skin rejuvenation effect through its interaction with CD44 receptors, favoring the proliferation of dermal fibroblasts and the release of extracellular matrix proteins (type I and III collagen, sulfated GAGs, elastin) and preventing the release of inflammatory cytokines by epidermal melanocytes and keratinocytes

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