We get into what most people are missing: why GLP-1s alone arent enoughand how the real magic happens when you combine them with the right nutrition and strength training
The SELECT trial showed that semaglutide reduced major adverse cardiovascular events (heart attack, stroke, cardiovascular death) in adults with obesity and established cardiovascular disease, without requiring a diabetes diagnosis. The FLOW trial showed kidney benefits with semaglutide use in patients with type 2 diabetes and chronic kidney disease. Improvements in hard clinical outcomes like cardiac events, kidney disease, and death are commonly observed with GLP-1 use, and are due to both the direct effects of treating the obesity, and indirect effects of the medications themselves
Articles were excluded if they non-human trials or were secondary research methods including meta-analyses, systematic or non-systematic reviews, scoping reviews, narrative review and literature reviews
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High-end medications like Wegovy can reach $1,300 monthly without insurance
Written informed consent for participation in this study was provided by the participants' legal guardians/next of kin