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recently demonstrated that GLP-1s natriuretic effect, GLP-1-dependent angiotensin II suppression, and high renal GLP-1 extraction all depend specifically and fully on GLP-1 receptor activation

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doi: 10.1136/bmj.315.7109.629 29 HajeMNaoomK

Requirements usually include: (1) BMI 30 , or BMI 27 with at least one weight-related health condition (type 2 diabetes, high blood pressure, or high cholesterol per FDA labeling), (2) participation in a 6-month weight management program (diet, exercise, and lifestyle changes), (3) chart notes documenting BMI and health conditions, and (4) no contraindications such as personal/family history of medullary thyroid cancer or MEN2 syndrome (a rare genetic condition)

Sasaki, S., Iwata, H., Ishiguro, N., Habuchi, O

Other regulatory bodies (DOD, DEA) specify their own panels