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Confirming the molecule engages both receptors A dual agonist is only as good as the proof that it truly hits both targets

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M., Hernndez-Fernndez, F

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Investigators are particularly interested in determining the mechanisms by which effects observed in murine models relate to broader mammalian metabolic regulation, and whether different experimental conditions (young vs aged models, healthy vs metabolically compromised states) show differential responses to NNMT inhibition