glp-1 r Targeting GLP-1, GIP & GCG in Obesity and Type 2 Diabetes Research Full-length human GLP-1 receptor structure

Khavinson VKh, Lezhava TA, Monaselidze JR, Jokhadze TA, Dvalishvili NA, Bablishvili NK, Trofimova SV

With monthly infusions and a three-month supply of Nicotinamide mononucleotide (NMN), your body will be well-supported in maintaining vitality

doi: 10.1146/annurev-immunol-041015-055605 94 CrottyS

Key features: Neutralizes free radicals and reduces oxidative stress

Its protective mechanism may involve the activation of the Nrf2/ARE and PI3K/Akt pathways, thereby reducing inflammation, oxidative stress, and apoptosis, which helps mitigate the progression of diabetic cardiomyopathy

It is specifically known for its ability to reduce excess abdominal fat (visceral adipose tissue) in individuals with HIV-associated lipodystrophy, but it is also researched for other potential metabolic and cognitive benefits