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Effectiveness of semaglutide versus liraglutide for treating post-metabolic and bariatric surgery weight recurrence

Both semaglutide GLP-1 and Zepbound are highly effective prescription medications approved for weight management, but individual results may vary

Wang, L., Xu, R., Kaelber, D

Measurable weight loss usually becomes apparent by weeks 3-4

71.2 lbs on average) Retatrutide 9mg: 26.4% body weight reduction Tirzepatide/Zepbound (Phase 3 comparison, not head-to-head): ~20.9% Semaglutide/Wegovy (Phase 3 comparison, not head-to-head): ~14.9% Placebo: ~2.1% Note: These figures come from separate Phase 3 trials and are not direct head-to-head comparisons

GLP-1 Bridge is a workaround, since it operates outside the Part D benefit, runs on CMSs demonstration authority, and expires on December 31, 2027