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However, the FDA label explicitly states that "it is unknown whether GLP-1 receptor agonists cause thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans, as the human relevance of GLP-1 receptor agonist-induced rodent thyroid C-cell tumors has not been determined." The rodent thyroid has substantially more C-cells than the human thyroid, and rodents may be more susceptible to this effect

The injectable form (Wegovy for weight loss, Ozempic for diabetes) is the most studied and most commonly prescribed

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Additionally, these drugs are to be avoided in patients with a history of thyroid cancer, either themselves or in the family

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These claims often involve extensive review of medical records, autopsy findings, hospitalization history, prescription records, and expert medical opinions regarding causation