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Direct inactivation of the enzyme tyrosinase Switching off the production of the Eumelanin (gives darker complexion) Switching on the production of the Pheomelanin (gives brighter complexion) Sun exposure and oxidative stress can disrupt melanin levels, leading to an increase in Eumelanin for a darker complexion, and a decrease in Pheomelanin, resulting in a brighter tone

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Pediatr Nephrol 23(12):21592173

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