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In AD models, the CD47SIRP axis is markedly activated

Moossavi S, Besharat S, Sharafkhah M, et al

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Damluji, MD, PhD, MBA Published Mar 29, 2025 The SOUL trial, published in The New England Journal of Medicine on March 29, 2025, provides new evidence that once-daily oral semaglutide reduces the risk of major adverse cardiovascular events in adults with type 2 diabetes and a history of atherosclerotic cardiovascular disease, chronic kidney disease, or both

Its also important to avoid sudden changes in activity or diet without consulting your nurse practitioner

For some women, menopause can also increase insulin resistance, which may make fat loss slower and cravings more intense