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Practical Mitigation Strategies Start low and increase it gradually to minimise GI upsettitrate semaglutide from 0.25 mg weekly, increasing gradually every 4 weeks

The primary composite endpoint (cardiovascular death or worsening heart failure) was reached in 9,9% of the tirzepatide arm versus 15,3% of the placebo arm (HR 0,62, p=0,026)

These include: Nausea (the most common complaint, particularly during dose escalation) Vomiting Diarrhoea Constipation Decreased appetite These effects are generally dose-dependent and tend to be most pronounced during the initial weeks of treatment or following a dose increase

Many people are now seeking GLP-1 friendly foods, high-protein small meals, and nutrient-dense foods to align with these new eating patterns

They work by mimicking a naturally occurring hormone in your body called glucagon-like peptide-1 (GLP-1) , which plays an important role in regulating appetite, digestion, and blood sugar levels