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Leech CA, Dzhura I, Chepurny OG, Kang G, Schwede F, Genieser HG, and Holz GG

Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy

In many cases, fat will be removed from under the muscle

This seemingly small chemical modification brings profound functional changes: the acetylated thiol group is protected from oxidation and enzymatic breakdown, while the overall molecules lipophilicity is significantly enhanced, allowing it to cross biological membranes more easily