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10.3390/biom9100517 119 RileyD
Allan et al used the TriNetX EHR platform to evaluate the risk of developing dry and wet AMD compared with controls in 9,669 patients taking GLP-1 RA medications
Carnitine plays an essential role in the way that mitochondria use fats for fuel, and the study showed that mice deficient in a carnitine transporter, SLC25A45, didnt lose weight as easily on a GLP-1 RA medication.[ref] Related article: Carnitine genes GLP-1 Beyond Weight Loss: Heart Disease, Alzheimers, Cancer, and Immunity Recent studies show that the benefits of GLP-1 RA medications extend beyond weight loss
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Excess body fat, particularly around the abdominal area, can lead to chronic inflammation, which disrupts GLP-1 signalling