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This is a genuine gap in the safety dossier, not a minor technicality

The results of experimental studies in animal models echo the findings of the review, demonstrating acute and chronic effects consistent with observations in humans

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Collectively these data cast doubt as to the contribution of inhibition of complex 1 as the primary target and explanation for the therapeutic effects of metformin both as an anti-diabetic and as an anti-aging drug

No research program is without constraints, and acknowledging these limitations helps set appropriate expectations

When introduced into the body, ozone reacts with cell membranes of pathogens, disrupting their integrity and leading to their destruction