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System Xc - , a cystine/glutamate antiporter, functions as a transmembrane complex of light chain xCT ( SLC7A11 -encoded) and heavy chain 4F2hc (72)

The selective SMIs of transcriptional co-activators across different disease phenotypes, along with their mechanism of action, have been summarized in Table 3

BioMed Research International, 2014

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